Effect of Amlodipine on the Lipid Profile of Newly Diagnosed Hypertensive Patients
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 80
- 主要终点
- Measurement of Plasma High Density Lipoproteins Concentration
研究概览
简要总结
In this study, Amlodipine has been used to study its effects in newly diagnosed hypertensive patients.
详细描述
The incidence of hypertension is on the rise in developing countries like Pakistan. Different medications are used to decrease blood pressure with Amlodipine as one of the first-line drugs. It was proposed that due to interaction with calcium and thus luminal cholecystokinin releasing factor; Amlodipine might increase the cholesterol level and thus cause dyslipidemia.
Objective
In this regard, this study was conducted to look into the effects of Amlodipine in newly diagnosed cases of hypertension that had received no medication previously.
Methodology: Experimental study with a healthy control group with the sample size calculated out to be 80, comprising of an equal number of enrolment into case and control groups.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Care Provider)
入排标准
- 年龄范围
- 20 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- 未提供
研究组 & 干预措施
Newly Diagnosed Hypertensive patients
These are the patients that have been clearly diagnosed with diabetes for the first time.
干预措施: Amlodipine (Drug)
结局指标
主要结局
Measurement of Plasma High Density Lipoproteins Concentration
时间窗: Four Months
Measured as per protocols provided by the kit manufacturer.
Measurement of Plasma Triglyceride Concentration
时间窗: Four Months
Measured as per protocols provided by the kit manufacturer.
Measurement of Blood Glucose Concentration
时间窗: Four Months
Measured as per protocols provided by the kit manufacturer.
Measurement of Total Plasma Cholesterol Concentration
时间窗: Four Months
Measured as per protocols provided by the kit manufacturer.
Measurement of Plasma Low Density Lipoproteins Concentration
时间窗: Four Months
Measured as per protocols provided by the kit manufacturer.
次要结局
未报告次要终点
研究者
Shahid ali shah
Assistant Professor
Ayub Teaching Hospital