The Use of Five-strand Hamstring Autograft to Increase the Graft Size in Anterior Cruciate Ligament Reconstruction - a Prospective Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 62
- 主要终点
- Mean graft diameter
研究概览
简要总结
Anterior cruciate ligament (ACL) reconstruction is one of most commonly performed orthopaedic surgeries. Several options for graft choice are available and autologous single bundle hamstring graft is most commonly used. Variability exists among patients in terms of hamstring size, and therefore the graft diameter. Recently there has been an increasing amount of literature correlating the hamstring graft diameter with the graft failure rate [1-4]. They concluded that graft exceeding 8mm in diameter is associated with a significant lower risk of graft failure. There has been study showing that Asian patients were indeed 'different' from the Caucasians. Ho et al published his findings on Singaporean patients showing that the median graft diameters for female and male patients were 7mm and 8mm respectively [5]. A retrospective review our patients undergoing ACL reconstruction in our department over the past 10 years has shown that the mean graft diameter was 7.8mm (range, 5.5-10mm).
The conventional way of four-strand hamstring autograft is done by doubling both the semitendinosus and gracilis tendons to provide a quadrupled graft. Several techniques have been described to increase the size of the hamstring graft. One of those is the -strand hamstring graft, in which the longer semitendinosus tendon is tripled with the shorter gracilis tendon doubled to produce a 5-strand configuration. We hypothesized that the 5-strand hamstring graft would provide a graft of significantly larger diameter than the conventional quadrupled autograft.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 50 Years(Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 18-50
- •Symptoms and physical examinations consistent with ACL deficiency and magnetic resonance imaging indicating ACL injury
排除标准
- •Previous surgeries in the operated knee
- •Revision ACL reconstruction
- •Contralateral ACL injury
- •Concomitant posterior cruciate ligament / collateral ligament surgeries in the operated knee
结局指标
主要结局
Mean graft diameter
时间窗: Intra-operative
次要结局
- Clinical measures of knee function and structure(Post-operative 3 months, 6 months, 9 months, 12 months, 18 months and 2 years.)
- ACL failure(Post-operative 3 months, 6 months, 9 months, 12 months, 18 months and 2 years.)
- Adverse event(Post-operative 3 months, 6 months, 9 months, 12 months, 18 months and 2 years.)
研究者
Keith Hay-Man Wan
Associate Consultant
Hospital Authority, Hong Kong
