Development of treatment for severe heart failure using autologous myoblast sheet
Phase 1
- Conditions
- Dilated cardiomyopathy, Ischemic cardiomyopathy
- Registration Number
- JPRN-UMIN000012906
- Lead Sponsor
- Osaka University Graduate School of Medicine, Cardiovascular surgery
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up continuing
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Not provided
Exclusion Criteria
1) Severe skeletal muscle disease 2) Severe infection 3) Alcoholic or drug addiction in recent six months 4) Malignancy 5) Virus infection (HIV, HBV, HCV,HTLV) 6) Pregnancy 7) Others
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Improvement of LV ejection fraction
- Secondary Outcome Measures
Name Time Method 1) Feasibility of myoblast sheet implantation 2) Improvement of regional function 3) LV reverse remodeling 4) Improvement of symptoms and grade of heart failure 5) Adverse event