Clinical implementation of advanced MRI techniques for localization and monitoring of sensorimotor and cognitive functions in patients with brain tumors
Completed
- Conditions
- hersentumoren (meningioom en laaggradige gliomen)brain tumorglioma
- Registration Number
- NL-OMON44896
- Lead Sponsor
- Sint Elisabeth Ziekenhuis
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 330
Inclusion Criteria
Patients: Adult patients diagnosed with a glioma or meningioma, age 18 - 75
Healthy subjects: age 18 - 75
Exclusion Criteria
Patients: metal objects in or around the body (braces, pacemaker, metal fragments) that are incompatible with MRI scan procedure
Healthy subjects: metal objects in or around the body (braces, pacemaker, metal fragments) that are incompatible with MRI scan procedure
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>study 1.1: development of cognitive test paradigms suitable for fMRI, that<br /><br>provide behavioral measurements that correlate with neuropsychological<br /><br>performance<br /><br><br /><br>study 1.2: application in healthy controls of cognitive fMRI protocols based on<br /><br>the best performing test paradigms from study 1.1 in order to test for<br /><br>robustness and reliability<br /><br><br /><br>study 2.1: application in patient cohorts of cognitive best performing fMRI<br /><br>protocols developed in study 2.1 to test for correlation of brain activity<br /><br>measures that correlate significantly with neuropsychological performance. </p><br>
- Secondary Outcome Measures
Name Time Method <p>NA</p><br>