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Clinical Trials/NCT07273682
NCT07273682
Not yet recruiting
Not Applicable

A Nurse-facilitated Interdisciplinary Transitional Care Programme for Childhood Cancer Survivors and Their Parents to Improve Symptom Management: a Feasibility Randomised Waitlist-controlled Trial

The Hong Kong Polytechnic University0 sites68 target enrollmentStarted: July 1, 2026Last updated:

Overview

Phase
Not Applicable
Status
Not yet recruiting
Enrollment
68
Primary Endpoint
Screening rate

Overview

Brief Summary

This study aims to evaluate the feasibility and preliminary effectiveness of a nurse-facilitated interdisciplinary transitional care programme, based on the Omaha system, for Chinese childhood cancer survivors (CCSs) and their parents in Hong Kong. Investigators will conduct a two-arm, randomized waitlist-controlled trial at the Hong Kong Children's Hospital, the only local center for CCS follow-up. Sixty-eight dyads (CCS aged 13-18 and a parent) will be randomized to either the 12-week nurse-led intervention or usual care. The intervention includes an initial face-to-face assessment and regular follow-ups via Zoom, focusing on symptom management, health education, and self-care empowerment, with referrals to other professionals as needed. The control group receives standard discharge care and educational materials, and will be offered the intervention after data collection. Outcomes will be assessed at baseline, and 3 and 6 months post-intervention, including symptom management, quality of life, caregiver burden, self-efficacy, and emergency department visits. Feasibility will be evaluated by recruitment, retention, attendance, and data completeness rates. If effective, this programme could improve transitional care and symptom management for CCSs and their families, and inform clinical practice and policy in Hong Kong and beyond.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Crossover
Primary Purpose
Supportive Care
Masking
Single (Outcomes Assessor)

Eligibility Criteria

Ages
13 Years to 18 Years (Child, Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Screening rate

Time Frame: Baseline

Number of dyads screened divided by number of dyads available for screening.

Eligibility rate

Time Frame: Baseline

Number of dyads eligible divided by number of dyads screened.

Recruitment rate

Time Frame: Baseline

Number of eligible dyads agree to join divided by number of eligible dyads.

Randomization rate

Time Frame: Baseline

Number of dyads being randomized divided by number of participating dyads.

Intervention attendance rate

Time Frame: Immediately after the intervention completion

Number of dyads who complete the intervention divided by number of dyads in the intervention group.

Missing data

Time Frame: Baseline, immediately after the intervention completion, 3 months after the intervention completion, 6 months after the intervention completion

Percentage of missing data

Adverse events

Time Frame: During the study period including 12-week intervention and 6 months follow-up

Number of unfavourable events and/or worsening reported.

Retention rate

Time Frame: Baseline, immediately after the intervention completion, 3 months after intervention completion, 6 months after intervention completion

Number of dyads remaining in the study divided by number of dyads being randomized.

Completion rate

Time Frame: Baseline, immediately after the intervention completion, 3 months after the intervention completion, 6 months after the intervention completion

Number of dyads who complete the questionnaire divided by number of questionnaires distributed.

Secondary Outcomes

  • Cancer-related symptoms in CCSs(Baseline, immediately after the intervention completion, 3 months after the intervention completion, 6 months after the intervention completion)
  • CCSs' quality of life (QoL)(Baseline, immediately after the intervention completion, 3 months after the intervention completion, 6 months after the intervention completion)
  • Caregiver burden of parents(Baseline, immediately after the intervention completion, 3 months after the intervention completion, 6 months after the intervention completion)
  • Caregiving competence of parents(Baseline, immediately after the intervention completion, 3 months after the intervention completion, 6 months after the intervention completion)
  • Parental quality of life (QoL)(Baseline, immediately after the intervention completion, 3 months after the intervention completion, 6 months after the intervention completion)
  • Number of emergency department (ED) visits(During the study period including 12-week intervention and 6 months follow up)

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Dr Eva Ho

associate professor

The Hong Kong Polytechnic University

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