Early NCPAP Before Surfactant Treatment in Very Preterm Infants With RDS
Completed
- Conditions
- Surfactant Treatment,Nasal Continuous Positive Airway Pressure,Preterm Infants,Respiratory Distress Syndrome,Bronchopulmonary Dysplasia
- Registration Number
- NCT01996670
- Lead Sponsor
- Xiangya Hospital of Central South University
- Brief Summary
We hypothesis a period of early NCPAP before surfactant treatment is effective for treating RDS and preventing BPD in very premature infants.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 683
Inclusion Criteria
- All enrolled infants were able to breathe at 5 min of age, had evidence of respiratory distress, unable to receive surfactant therapy, and were administrated with early NCPAP as the initial treatment
Exclusion Criteria
- Exclusion criteria were endotracheal intubation for resuscitation or insufficient respiratory drive, died in the first 24 hours after birth, known genetic disorders, potentially life-threatening conditions unrelated to prematurity, and premature rupture of membranes (PROM) for >3 weeks.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method death or bronchopulmonary dysplasia 24 hours after birth
- Secondary Outcome Measures
Name Time Method