A Muti-centre Prospective Observational Study on Postoperative Temperature Monitoring In Patients With Brain Trauma
试验速览
- 阶段
- 不适用
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- Change of Brain Temperature
研究概览
简要总结
This prospective observational study is designed to investigate the relationship between brain temperature, axillary temperature, rectal temperature, and bladder temperature of postoperative patients with brain trauma, and the relationship between brain temperature and prognosis. This study is conducted based on the following important assumptions. First, brain temperature of postoperative patients with brain trauma should be higher than the axillary temperature, rectal temperature and bladder temperature. Second, the consistency of brain temperature and bladder temperature is better than the consistency of brain temperature and axillary temperature, as well as that of brain temperature and rectal temperature. Third, brain temperature can help clinicians to predict the prognosis of patients with brain trauma. Therefore, brain temperature monitoring is significant in postoperative intensive care and treatment of patients with brain trauma.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Clinical or radiological diagnosis is brain trauma;
- •The patient has surgical indications, and the patient or his/her family are willing to undergo operation including brain temperature monitoring probe implantation;
- •Informed consent is obtained from the patient's family.
排除标准
- •At the time of admission there are serious systemic diseases, including severe infections, immune system diseases, blood system diseases, infectious diseases, severe liver and kidney dysfunction, malignant tumors, etc;
- •Pregnant or lactating women;
- •There are other brain tumors or cerebrovascular disease in the brain at the same time;
- •There is a history of drug or alcohol abuse;
- •Within 3 months before admission, live vaccines were inoculated.
结局指标
主要结局
Change of Brain Temperature
时间窗: Change from Baseline Brain Temperature at 1 week
Change of Rectal Temperature
时间窗: Change from Baseline Rectal Temperature at 1 week
Change of Bladder Temperature
时间窗: Change from Baseline Bladder Temperature at 1 week
Glasgow Outcome Scale
时间窗: 1 month
An objective assessment of the recovery of patients with brain trauma
Change of Axillary Temperature
时间窗: Change from Baseline Axillary Temperature at 1 week
次要结局
未报告次要终点