An intervention study to improve therapeutic compliance in adult patients with eosinophilic esophagitis.

Recruiting

• Conditions: allergic esophagitis; Eosinophilic esophagitis; 10017969

• Registration Number: NL-OMON51510
• Lead Sponsor: Amsterdam UMC

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 72

Inclusion Criteria

- Written informed consent
- Male or female patient
- Age >18 years
- Previous diagnosis of EoE, confirmed by histopathology, with the presence of
>15 eosinophilic granulocytes per high power field (hpf) in esophageal biopsies
- Current maintenance treatment for EoE with a PPI or swallowed topical
corticosteroids or about to start with these maintenance medications as decided
during regular clinical practice

Exclusion Criteria

- Severe and clinically unstable concomitant disease that may interfere with
the subject*s ability to participate in the study
- Receive investigational treatment during the study
- Dilation of esophagus required
- Insufficient Dutch or English language skills to understand patient
information leaflets

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Differences in treatment adherence between both groups after 12 weeks, 6 months<br /><br>and 12 months.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>- Differences in self-reported treatment adherence (measured by MARS<br /><br>questionnaire, 8-point MMAS, BMQ, IPQ) after 12 weeks, 6 months and 12 months.<br /><br>- Change in clinical symptoms (measured by SDI, DSQ) after 12 weeks, 6 months<br /><br>and 12 months.</p><br>