PRagmatic Trial Of Messaging to Providers About Treatment of Heart Failure at Inova
- Conditions
- Heart Failure
- Interventions
- Other: Best Practice Advisory using Electronic Health Record
- Registration Number
- NCT05433220
- Lead Sponsor
- Inova Health Care Services
- Brief Summary
A randomized, single-blind intervention trial to test the comparative effectiveness of an electronic health record best practice advisory system that informs clinicians of guideline-indicated and FDA-approved heart failure medications currently not prescribed to their patients with heart failure versus usual care (no alert and how things are done currently). The purpose of the alert is to stimulate appropriate medication prescription for patients with heart failure and a reduced ejection fraction. This will be done across outpatient Inova clinics and at the five Inova hospitals.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 5000
- Age>18 Years
- Seen by a Cardiologist in an Inova clinic or Inova hospital setting
- Left Ventricular Ejection Fraction ≤40%
- Opted out of EHR-based research
- Hospice care
- Already receiving maximally titrated doses of each of the four classes of evidence- based HFrEF medical therapy
- Prior heart transplant
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Alert when provider is entering orders Best Practice Advisory using Electronic Health Record -
- Primary Outcome Measures
Name Time Method Increased use of GDMT in patients with Heart Failure with Reduced Ejection Fraction 30 days after randomization The primary outcome for the trial will be the proportion of patients with HFrEF who have an increase in the number of prescribed evidence-based therapies for HFrEF (beta-blockers, ACE-I/ARB/ARNI, MRA, SGLT2i) 30 days after randomization.
- Secondary Outcome Measures
Name Time Method All-cause hospitalization and all-cause mortality at 30 days 30 days Outcomes will be determined by review of medical, hospital, and billing records.
All-cause hospitalization and all-cause mortality at 90 days 90 days Outcomes will be determined by review of medical, hospital, and billing records.
All-cause hospitalization and all-cause mortality at 180 days 180 days Outcomes will be determined by review of medical, hospital, and billing records.
All-cause hospitalization and all-cause mortality at 1 year 1 year Outcomes will be determined by review of medical, hospital, and billing records.
Trial Locations
- Locations (1)
Inova Health System
🇺🇸Falls Church, Virginia, United States