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临床试验/NCT07325682
NCT07325682Enrolling By Invitation不适用

Personalized, Scientifically Based Technologies in the Diagnosis and Treatment of SARS-CoV-2 as a Possible Cervical Cancer Risk Factor

Oncology Center,Ministry Of Heath,Uzbekistan1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2025年4月30日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
Enrolling By Invitation
发起方
入组人数
30
试验地点
1
主要终点
Number of Participants With Bioelectrical Patterns Consistent With Viral Antigen Persistence

研究概览

简要总结

This study aims to evaluate the diagnostic value of an electroacupuncture-based method for detecting viral persistence (human papillomavirus and SARS-CoV-2) in patients with cervical cancer. The study investigates whether persistent viral signatures can be identified through measurable electrodiagnostic responses at acupuncture points associated with organ systems affected by chronic viral infection. The goal is to assess the feasibility, reproducibility, and potential clinical relevance of this diagnostic approach in oncology patients.

详细描述

This study investigates the diagnostic potential of an electroacupuncture-based measurement method to detect viral persistence in patients with cervical cancer. Increasing evidence indicates that oncologic processes may be influenced by chronic viral activity, including persistent human papillomavirus (HPV) infection and, in some cases, secondary viral signatures such as SARS-CoV-2. Although HPV is the primary etiologic agent in cervical cancer, clinical observations suggest that long-term viral presence may contribute to variations in disease behavior, immune dysfunction, and treatment response.

The diagnostic method used in this study is based on measurement of electrical parameters at standardized acupuncture points. These points are functionally connected to organ systems involved in chronic viral disease. Changes in their electrical characteristics may reflect physiological responses associated with viral persistence. The technique has been previously developed and refined in clinical practice and has demonstrated reproducibility in identifying characteristic response patterns in patients with viral and post-viral conditions.

This study aims to evaluate whether measurable electrodiagnostic responses correlate with persistent viral signatures in cervical cancer patients. All participants undergo standardized diagnostic measurements performed under controlled conditions. The study does not involve therapeutic intervention, drug administration, or device implantation. Only diagnostic data are collected.

The primary objective is to assess whether this method can reliably identify patterns consistent with viral persistence. Secondary objectives include evaluating repeatability of measurements, describing characteristic profiles in this patient population, and assessing feasibility of integrating this diagnostic approach into clinical oncology settings.

This research is expected to contribute to a better understanding of viral involvement in cancer microenvironments and to support the development of non-invasive diagnostic tools for evaluating viral activity in oncologic patients.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Diagnostic
盲法
None

盲法说明

Diagnostic evaluation of viral persistence using EAV-based measurement of viral activity in cervical cancer patients.

入排标准

年龄范围
21 Years 至 70 Years(Adult, Older Adult)
性别
Female
接受健康志愿者

入选标准

  • Histologically confirmed cervical cancer (FIGO stage IIIA-IVA)
  • Age ≥21 years
  • ECOG performance status adequate for diagnostic procedures
  • Adequate organ function
  • Ability to provide informed consent

排除标准

  • Poor renal function (elevated creatinine)
  • Significant liver dysfunction (elevated bilirubin or liver enzymes)
  • Severe cardiovascular or pulmonary disease
  • Pregnancy or breastfeeding
  • Severe mental illness or inability to provide informed consent
  • Known non-compliance or substance abuse

研究组 & 干预措施

Diagnostic Group

Experimental

Non-invasive diagnostic method assessing bioelectrical response patterns associated with viral markers in patients with cervical cancer.

干预措施: Electroacupuncture (Diagnostic Test)

结局指标

主要结局

Number of Participants With Bioelectrical Patterns Consistent With Viral Antigen Persistence

时间窗: At enrollment (single diagnostic session)

Diagnostic assessment to identify bioelectrical response patterns associated with viral antigen persistence in cervical cancer patients using a non-invasive bioelectrical testing approach.

次要结局

未报告次要终点

研究者

发起方
Oncology Center,Ministry Of Heath,Uzbekistan
申办方类型
Other
责任方
Principal Investigator
主要研究者

Naylya Djumaeva

Principal Investigator

Oncology Center,Ministry Of Heath,Uzbekistan

研究点 (1)

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