Is Recombinant Growth Hormone Therapy Associated With Increased Intraoccular Pressure?

• Conditions: Growth Hormone Treatment; Glaucoma
• Interventions: Other: Measuring intraoccular pressure

• Registration Number: NCT00867971
• Lead Sponsor: Assaf-Harofeh Medical Center

Brief Summary

Recombinant growth hormone is a common therapy in the pediatric population. A number of associated side effects have been described. Several years ago, a case report was published concerning a child that was treated with RGH and developed acute glaucoma. To date no study has evaluated the connection.

Detailed Description

Not available

Study Timeline

• Status Verified: 2009-02
• Study Start: 2009-02
• Study First Submitted: 2009-03-22
• Study First Submitted QC: 2009-03-22
• Last Update Submitted: 2009-03-22
• Study First Posted: 2009-03-24
• Last Update Posted: 2009-03-24
• Primary Completion: 2010-10
• Study Completion: 2010-10

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Age 6-18 years
• treatment with recombinant growth hormone

Exclusion Criteria

• Underlying Chronic diseases
• Family history of eye diseases
• elevated occular pressure prior to starting treatment

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
RGH treated	Measuring intraoccular pressure	-
Starting treatment with RGH	Measuring intraoccular pressure	-

Primary Outcome Measures

Name	Time	Method
Intraoccular pressure in children treated with RGH	2 years

Trial Locations

Locations (1)

Assaf harofeh medical center; 🇮🇱 Zerifin, Israel