Impact of Different Types of Physical Activity in Patients With Chronic Inflammatory Bowel Disease
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Inflammatory Bowel Diseases
- Sponsor
- University of Liege
- Enrollment
- 24
- Locations
- 1
- Primary Endpoint
- Short health scale questionnaire
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
This is a prospective interventional study. The investigators will include patients in clinical remission who are on stable treatment. These IBD patients will be followed to analyze the effects of physical activity on their inflammatory disease. Different exercises will be offered to two separate groups of randomly distributed patients: the first group will perform muscle building exercises while the other group will be offered aerobic exercises.There will also be a control group that does not initially benefit from a specific physical activity program. However, this group will be integrated into one of the other two groups after the 10-week follow-up. All three groups will perform the same baseline tests. These will be of different types: physical tests, biological tests and quality of life questionnaires.
Investigators
Gofflot Amandine
Principal Investigator
University of Liege
Eligibility Criteria
Inclusion Criteria
- •Patients in remission defined by a Harvey Bradshaw Index 5 in Crohn's disease (CD) and a clinical Mayo 3 with no sub-score \>1 in ulcerative colitis (RCUH) with stable treatment, without corticosteroid for 4 months.
- •Patients accepting the study protocol
Exclusion Criteria
- •Patients suffering from other pathologies (at the level of the digestive system, the cardiovascular system, as well as the musculoskeletal system: recent knee plasty, recent knee fractures, etc.), which can interfere with planned tests and activity programs.
- •Patients with more than 3 hours of sports activity per week
- •Pregnant, pregnant or nursing patients
Outcomes
Primary Outcomes
Short health scale questionnaire
Time Frame: Week 20
Participants will complete a questionnaire to evaluate the level of the inflammatory bowel disease
EQ5D questionnaire
Time Frame: Week 20
Participants will complete a questionnaire on their level of health
Short Food Frequency Questionnaire
Time Frame: Week 20
Participants will complete a questionnaire on their dietary habits
Progressive effort test on bicycle ergometer (VO2 max)
Time Frame: through study completion, an average of 40 weeks
This test allows to measure VO2 in ml/min/kg (thanks to respiratory gases)
Progressive effort test on bicycle ergometer (Power)
Time Frame: through study completion, an average of 40 weeks
This test allows to measure maximum aerobic power in Watt.
Blood sample
Time Frame: through study completion, an average of 40 weeks
This type of tests includes biological monitoring to obtain information on biological parameters.
Saddle analysis
Time Frame: through study completion, an average of 40 weeks
This type of tests includes biological monitoring to obtain information on biological parameters.
IBD-F
Time Frame: Week 20
Participants will complete a questionnaire on fatigue perceived.
Progressive effort test on bicycle ergometer (Heart rate)
Time Frame: through study completion, an average of 40 weeks
This test allows to measure resting and maximum heart rate (thanks to an ECG) and maximum aerobic power in Watt.
Maximum force test (N/m)
Time Frame: through study completion, an average of 40 weeks
This test will be performed using an isokinetic dynamometer. This evaluation will allow us to determine the maximum force of the quadriceps and hamstrings of each participant in N/m.
Godin Leisure Time exercise questionnaire
Time Frame: Week 1
Participants will complete a questionnaire on the level of physical activity
Metabolic Equivalent Task questionnaire
Time Frame: Week 20
Participants will complete a questionnaire on the level of inactivity