Impact of Different Types of Physical Activity in Patients With Chronic Inflammatory Bowel Disease
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 24
- 试验地点
- 1
- 主要终点
- Progressive effort test on bicycle ergometer (Power)
研究概览
简要总结
This is a prospective interventional study. The investigators will include patients in clinical remission who are on stable treatment. These IBD patients will be followed to analyze the effects of physical activity on their inflammatory disease. Different exercises will be offered to two separate groups of randomly distributed patients: the first group will perform muscle building exercises while the other group will be offered aerobic exercises.There will also be a control group that does not initially benefit from a specific physical activity program. However, this group will be integrated into one of the other two groups after the 10-week follow-up. All three groups will perform the same baseline tests. These will be of different types: physical tests, biological tests and quality of life questionnaires.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients in remission defined by a Harvey Bradshaw Index 5 in Crohn's disease (CD) and a clinical Mayo 3 with no sub-score >1 in ulcerative colitis (RCUH) with stable treatment, without corticosteroid for 4 months.
- •Patients accepting the study protocol
排除标准
- •Patients suffering from other pathologies (at the level of the digestive system, the cardiovascular system, as well as the musculoskeletal system: recent knee plasty, recent knee fractures, etc.), which can interfere with planned tests and activity programs.
- •Patients with more than 3 hours of sports activity per week
- •Pregnant, pregnant or nursing patients
研究组 & 干预措施
Endurance training group
干预措施: Endurance training (Other)
Resistance training group
干预措施: Resistance training (Other)
Control group
结局指标
主要结局
Progressive effort test on bicycle ergometer (Power)
时间窗: through study completion, an average of 40 weeks
This test allows to measure maximum aerobic power in Watt.
Progressive effort test on bicycle ergometer (Heart rate)
时间窗: through study completion, an average of 40 weeks
This test allows to measure resting and maximum heart rate (thanks to an ECG) and maximum aerobic power in Watt.
Short health scale questionnaire
时间窗: Week 20
Participants will complete a questionnaire to evaluate the level of the inflammatory bowel disease
EQ5D questionnaire
时间窗: Week 20
Participants will complete a questionnaire on their level of health
Short Food Frequency Questionnaire
时间窗: Week 20
Participants will complete a questionnaire on their dietary habits
Progressive effort test on bicycle ergometer (VO2 max)
时间窗: through study completion, an average of 40 weeks
This test allows to measure VO2 in ml/min/kg (thanks to respiratory gases)
Blood sample
时间窗: through study completion, an average of 40 weeks
This type of tests includes biological monitoring to obtain information on biological parameters.
Saddle analysis
时间窗: through study completion, an average of 40 weeks
This type of tests includes biological monitoring to obtain information on biological parameters.
IBD-F
时间窗: Week 20
Participants will complete a questionnaire on fatigue perceived.
Maximum force test (N/m)
时间窗: through study completion, an average of 40 weeks
This test will be performed using an isokinetic dynamometer. This evaluation will allow us to determine the maximum force of the quadriceps and hamstrings of each participant in N/m.
Godin Leisure Time exercise questionnaire
时间窗: Week 1
Participants will complete a questionnaire on the level of physical activity
Metabolic Equivalent Task questionnaire
时间窗: Week 20
Participants will complete a questionnaire on the level of inactivity
Progressive effort test on bicycle ergometer (Heart rate)
时间窗: day 1
This test allows to measure resting and maximum heart rate (thanks to an ECG) and maximum aerobic power in Watt.
Progressive effort test on bicycle ergometer (VO2 max)
时间窗: day 1
This test allows to measure VO2 in ml/min/kg (thanks to respiratory gases)
Progressive effort test on bicycle ergometer (Power)
时间窗: day 1
This test allows to measure maximum aerobic power in Watt.
Maximum force test (N/m)
时间窗: Day 1
This test will be performed using an isokinetic dynamometer. This evaluation will allow us to determine the maximum force of the quadriceps and hamstrings of each participant in N/m.
Blood sample
时间窗: Day 1
This type of tests includes biological monitoring to obtain information on biological parameters.
Saddle analysis
时间窗: Day 1
This type of tests includes biological monitoring to obtain information on biological parameters.
IBD-F
时间窗: Week 1
Participants will complete a questionnaire on fatigue perceived.
IBD-F
时间窗: Week 10
Participants will complete a questionnaire on fatigue perceived.
Metabolic Equivalent Task questionnaire
时间窗: Week 1
Participants will complete a questionnaire on the level of inactivity
Metabolic Equivalent Task questionnaire
时间窗: Week 10
Participants will complete a questionnaire on the level of inactivity
Short Food Frequency Questionnaire
时间窗: Week 1
Participants will complete a questionnaire on their dietary habits
Short Food Frequency Questionnaire
时间窗: Week 10
Participants will complete a questionnaire on their dietary habits
EQ5D questionnaire
时间窗: Week 1
Participants will complete a questionnaire on their level of health
EQ5D questionnaire
时间窗: Week 10
Participants will complete a questionnaire on their level of health
Short health scale questionnaire
时间窗: Week 1
Participants will complete a questionnaire to evaluate the level of the inflammatory bowel disease
Short health scale questionnaire
时间窗: Week 10
Participants will complete a questionnaire to evaluate the level of the inflammatory bowel disease
次要结局
未报告次要终点
研究者
Gofflot Amandine
Principal Investigator
University of Liege