Diagnostic accuracy of neuroblastoma patient imaging with [18F]-mFBG PET-CT compared to [123I]mIBG scanning
Completed
- Conditions
- neuroblastoma
- Registration Number
- NL-OMON28070
- Lead Sponsor
- Prinses Máxima Centrum for pediactric cancer
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 20
Inclusion Criteria
patients with a (clinical suspicion of) neuroblastoma who are referred for [123I] mIBG imaging, 0-18 years of age
Exclusion Criteria
pregnancy of the patient and above 18 years old
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary study endpoints are the number of lesions and sites of disease detected with 18F-mFBG PET-CT<br>compared to the current imaging standard of care, 123I-mIBG scan using the SIOPEN imaging scoring method for<br>skeletal lesions and the total number of detected soft tissue lesions
- Secondary Outcome Measures
Name Time Method o Determine optimum imaging time of 18F-mFBG PET CT(60 min vs 120-150 min post injection)<br>o Determine the estimation of radiation absorbed dose of 18F-mFBG<br>o Adverse events of 18F-mFBG injection and PET CT s