Ultrasonographic Evaluation of Fetal Adrenal Gland in Cases of Threatened Preterm Labor

Completed

• Conditions: Preterm Labor
• Interventions: Diagnostic Test: three dimensional ultrasound; Diagnostic Test: color Doppler

• Registration Number: NCT03251794
• Lead Sponsor: Assiut University

Brief Summary

Preterm birth continues to be a major public health problem with lasting family and societal repercussions. Despite tremendous research effort, prevention strategies have failed, and the prevalence of preterm birth in the United States reached 12.3% in 2003.

Prematurity causes 70% of fetal/neonatal deaths. 11.4% of births are at \< 37 weeks' gestation. The rate of prematurity increases dramatically with the number of fetuses - singletons 10%; twins 54.9%; and triplets 93.6%

Detailed Description

Not available

Study Timeline

• Study Start: 2017-03-01
• Study First Submitted: 2017-08-13
• Study First Submitted QC: 2017-08-13
• Study First Posted: 2017-08-16
• Primary Completion: 2018-03-15
• Study Completion: 2018-04-18
• Status Verified: 2018-06
• Last Update Submitted: 2018-06-26
• Last Update Posted: 2018-06-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 30

Inclusion Criteria

1. singleton fetus less than 37 weeks of gestation

2. women diagnosed to having Threatened preterm labor.

   1. presence of uterine contraction (at least 4 in 20 min or 8 in 60 min )
   2. cervical effacement <80 %
   3. cervical dilatation <1 cm

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Exclusion Criteria

1. suspected fetal growth restriction,
2. maternal medical complications,
3. presence of fetal heart rate abnormalities at enrollment.
4. Preterm Premature rupture of membranes
5. Placenta previa
6. Lower urinary tract infection or genital infection
7. Fetal congenital anomaly

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
threatened preterm labor	three dimensional ultrasound	women presented to the reception unit from 28-37 weeks by regular contractions and opened cervix
threatened preterm labor	color Doppler	women presented to the reception unit from 28-37 weeks by regular contractions and opened cervix

Primary Outcome Measures

Name	Time	Method
the volume of adrenal gland	5 minutes	measurement by three dimensional ultrasound

Trial Locations

Locations (1)

Assiut Faculty of Medicine; 🇪🇬 Assiut, Egypt