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High Flow Nasal Oxygen Versus Usual Care in COPD Pulmonary Rehabiliation

Not Applicable
Conditions
Chronic Obstructive Pulmonary Disease
Registration Number
NCT03940040
Lead Sponsor
Changi General Hospital
Brief Summary

To compare the effects of high flow nasal oxygen with usual care during an outpatient 6-week pulmonary rehabilitation program after hospitalization for COPD exacerbation.

Detailed Description

This is a pilot randomized controlled trial to compare the effects of high flow nasal oxygen with usual care during an outpatient 6-week pulmonary rehabilitation program after hospitalization for COPD exacerbation.

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
22
Inclusion Criteria
  1. Age 21 years and above
  2. Known diagnosis of COPD based on history AND spirometry demonstrating post bronchodilator FEV1/FVC ratio <0.7
  3. Currently admitted inpatient for an acute COPD exacerbation as the primary diagnosis
  4. Fit to participate in exercise therapy as determined by both physician and physiotherapist
  5. Has the mental capacity to follow instructions
  6. Experience shortness of breath on exertion
  7. Have decreased ability to carry out activities due to shortness of breath
  8. Willing to participate in the exercise program
Exclusion Criteria
  1. Uncontrolled/ unstable medical conditions such as severe chronic heart failure that make exercise unsafe
  2. Pulmonary disorder other than COPD
  3. Physical conditions that preclude the ability to participate in exercise or may impair exercise performance.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
6-minute walk distance6 weeks

It is the maximum distance walked in 6 minutes

Secondary Outcome Measures
NameTimeMethod
Hospital Anxiety Depression Scale3 weeks, 6 weeks and 1 month after completion of program

This scale has 2 subscale scores of 1) Depression 2) Anxiety. Scores of 0-7 = Normal, 8-10 = Borderline, 11-21 = Abnormal

COPD Assessment Test score3 weeks, 6 weeks and 1 month after completion of program

Chronic obstructive pulmonary disease assessment test (CAT) score

Respiratory function test3 weeks, 6 weeks and 1 month after completion of program

It is a test of respiratory function

6-minute walk distance3 weeks and 1 month after completion of program

It is the maximum distance walked in 6 minutes

Trial Locations

Locations (1)

Changi General Hospital

🇸🇬

Singapore, Singapore

Changi General Hospital
🇸🇬Singapore, Singapore
Yingjuan Mok, MBBS
Contact
68502600
mok.yingjuan@singhealth.com.sg
Nur Shameerah Abdul Halim
Contact
68502600
Nur_Shameerah@cgh.com.sg

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