High Flow Nasal Oxygen Versus Usual Care in COPD Pulmonary Rehabiliation
- Conditions
- Chronic Obstructive Pulmonary Disease
- Registration Number
- NCT03940040
- Lead Sponsor
- Changi General Hospital
- Brief Summary
To compare the effects of high flow nasal oxygen with usual care during an outpatient 6-week pulmonary rehabilitation program after hospitalization for COPD exacerbation.
- Detailed Description
This is a pilot randomized controlled trial to compare the effects of high flow nasal oxygen with usual care during an outpatient 6-week pulmonary rehabilitation program after hospitalization for COPD exacerbation.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 22
- Age 21 years and above
- Known diagnosis of COPD based on history AND spirometry demonstrating post bronchodilator FEV1/FVC ratio <0.7
- Currently admitted inpatient for an acute COPD exacerbation as the primary diagnosis
- Fit to participate in exercise therapy as determined by both physician and physiotherapist
- Has the mental capacity to follow instructions
- Experience shortness of breath on exertion
- Have decreased ability to carry out activities due to shortness of breath
- Willing to participate in the exercise program
- Uncontrolled/ unstable medical conditions such as severe chronic heart failure that make exercise unsafe
- Pulmonary disorder other than COPD
- Physical conditions that preclude the ability to participate in exercise or may impair exercise performance.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method 6-minute walk distance 6 weeks It is the maximum distance walked in 6 minutes
- Secondary Outcome Measures
Name Time Method Hospital Anxiety Depression Scale 3 weeks, 6 weeks and 1 month after completion of program This scale has 2 subscale scores of 1) Depression 2) Anxiety. Scores of 0-7 = Normal, 8-10 = Borderline, 11-21 = Abnormal
COPD Assessment Test score 3 weeks, 6 weeks and 1 month after completion of program Chronic obstructive pulmonary disease assessment test (CAT) score
Respiratory function test 3 weeks, 6 weeks and 1 month after completion of program It is a test of respiratory function
6-minute walk distance 3 weeks and 1 month after completion of program It is the maximum distance walked in 6 minutes
Related Research Topics
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Trial Locations
- Locations (1)
Changi General Hospital
🇸🇬Singapore, Singapore
Changi General Hospital🇸🇬Singapore, SingaporeYingjuan Mok, MBBSContact68502600mok.yingjuan@singhealth.com.sgNur Shameerah Abdul HalimContact68502600Nur_Shameerah@cgh.com.sg