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Not yet recruiting
Phase 1
Expansion of virus specific lymphocytes for cell therapy in immunosuppressed patients submitted to bone marrow transplant - : Cell therapy for CMV infection in transplanted patients
Sociedade Beneficente Israelita Brasileira - Hospital Israelita Albert Einstein0 sitesMarch 20, 2019
ConditionsCytomegalovirus Infection
Overview
- Phase
- Phase 1
- Intervention
- Not specified
- Conditions
- Cytomegalovirus Infection
- Sponsor
- Sociedade Beneficente Israelita Brasileira - Hospital Israelita Albert Einstein
- Status
- Not yet recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients of both sexes. Patients who have undergone allogeneic bone marrow transplantation. Patients who have cytomegalovirus infection or reactivation without clinical improvement or CMV copy decline after at least 2 weeks of treatment with standard anti\-viral therapy.
Exclusion Criteria
- •Patients who have received ATG, Campath or other immunosuppressive monoclonal antibody in less than 28 days. Patients who have received infusion of donor lymphocytes in less than 28 days. Patients with other uncontrolled infections than cytomegalovirus. Patients with Grade II to IV active graft versus host disease (GVHD). Patients receiving corticosteroid therapy with equivalent or higher doses of prednisone 0\.5mg/kg.
Outcomes
Primary Outcomes
Not specified
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