Fish Oil, Exercise, and Mediterranean Diet on Metabolic Markers of Inactive Premenopausal Wome

Not Applicable

Completed

• Conditions: Metabolic Syndrome; Inflammation; Dyslipidemia; Diabetes; Obesity; Metabolic and Endocrine - Diabetes; Diet and Nutrition - Obesity

• Registration Number: ACTRN12612000529842
• Lead Sponsor: Stephen H. Boutcher, Ph.D.

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2012-05-18
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 30

Inclusion Criteria

Premenopausal, recreationally active but untrained (< 2.5 hours a week of physical activity) overweight or obese (all women except Asian women had a BMI > 25 and < 35 kg/meters squared, Asian women had a BMI >23 and <33 kg/meters squared) women were recruited from a university population.

Exclusion Criteria

Women were overweight or obese but otherwise healthy. Women were excluded if they had any of the following: diabetes, impaired glucose tolerance (fasting plasma glucose levels above 6.0 mmol/L), hypertension (blood pressure >140/90 mmHg), cardiovascular disease, psychiatric problems, history of alcohol abuse (intake of >500 g/wk in the last year), current or recent (in the past 3 years), smoking, certain medication use, symptoms of chronic or current infection, a chronic inflammatory condition, any thyroid condition, liver disease or malignancy, being pregnant or planning on becoming pregnant during the study.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Decrease risk of metabolic syndrome: lower total and central adiposity measured by either dual energy xray absorptiometry or a Tanita body composition scale, improved triglyceride, total cholesterol, low density lipoprotein, high density lipoproteins, and glucose levels measured by a Cholestech analyzer to detect whole blood levels, and blood pressure values measured by a manual sphygmomanometer. All the above mentioned variables were measured pre to post intervention. Improve hormone and inflammatory concentrations from plasma samples analyzed with High-Sensitivity Enzyme Immunoassays (hs-ELISA) and increase fitness levels assess with a cardiorespiratory fitness test on a cycle ergometer.[Pre, 6 and 12 weeks of the intervention]

Secondary Outcome Measures

Name	Time	Method
Improve the quality of the dietary intake through 24 hour dietary recalls analyzed using Foodworks software.[Pre, 6 and 12 weeks of the intervention]