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Sequential letrozole and human menopausal gonadotropins (HMG) : The effect of a novel super ovulation protocol on pregnancy rate in polycystic ovarian syndrome patients undergoing intracytoplasmic sperm injection. Randomized Controlled Trial

Phase 4
Completed
Conditions
polycystic ovary syndrome
Reproductive Health and Childbirth - Fertility including in vitro fertilisation
Registration Number
ACTRN12614000025639
Lead Sponsor
alexandria university , faculty of medicine
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Female
Target Recruitment
40
Inclusion Criteria

PCOS complaining of infertility
age between 20-35 years.
normal semen analysis according to WHO criteria

Exclusion Criteria

female with a previous history of pelvic surgery
endometriosi.
females with a previous history of failed ICSI

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
the number of oocytes obtained through ovum pickup by transvaginal ultrasound guided aspiration through identification of oocyte under microscopy after ovum pickup [Approximately 34 - 36 hours after HCG administration]; the number of mature oocytes through assessment of maturity criteria under microscopy using first polar body assessment [ 1-2 hours after ovum pick up]
Secondary Outcome Measures
NameTimeMethod
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