Parkinson's Progression Markers Initiative Online Study (PPMI Online)
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Parkinson Disease
- Sponsor
- Michael J. Fox Foundation for Parkinson's Research
- Enrollment
- 500000
- Locations
- 1
- Primary Endpoint
- Unified Parkinson's Disease Rating Scale Ib & II
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
Parkinson Progression Marker Initiative Online (PPMI Online) is an observational study collecting participant reported information from people with and without Parkinson's disease (PD), for the goal of better understanding risk and predictive factors for PD.
PPMI Online is part of the broader Parkinson Progression Marker Initiative aimed at identifying markers of disease progression for use in clinical trials of therapies to reduce progression of PD disability.
Detailed Description
PPMI is a broad program that is expanding the goals of the original PPMI study, and will include this PPMI Online protocol, as well the PPMI Clinical \[NCT04477785\], PPMI Remote, PPMI Digital protocols (with external regulatory oversight). All participants in PPMI may be asked to participate in one or all of these protocols and their enrollment in these studies may occur in varying order. PPMI participants may also be asked to participate in additional PPMI companion studies (as they are developed), which may only involve a subset of PPMI participants based on their cohort designation
Investigators
Caroline M Tanner
Protocol Co- Principal Investigator
University of California, San Francisco
Eligibility Criteria
Inclusion Criteria
- •Parkinson Disease (PD) Participants:
- •Male or female age 18 years or older.
- •Has received a diagnosis of Parkinson's disease
- •Participants without PD:
- •Male or female age 18 years or older.
- •Has not received a diagnosis of Parkinson's disease
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Unified Parkinson's Disease Rating Scale Ib & II
Time Frame: Baseline to 240 months
Evaluates self-reported motor and nonmotor Parkinson's disease symptoms