A clinical study on tooth movement and identifying the factors influencing it in patients with irregular teeth.

Not Applicable

Completed

• Conditions: Health Condition 1: null- MALOCCLUSIO

• Registration Number: CTRI/2018/05/013700
• Lead Sponsor: Dr S LALITHAPRIYA

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2019-01-21
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 26

Inclusion Criteria

1. Angleâ??s class I & II malocclusion that requires segmental maxillary canine retraction

2. There should be no intra- arch canine interference

3. Canine mesial Angulation 11degrees +/- 10 degrees.

4. Eruption of all permanent teeth in the both arch.

5. Absence of congenital missing of any permanent teeth except third molar.

6. Third molar might be missing/fully erupted/partially erupted/impacted.

7. Patients who needs extraction of either all first 1st premolars or only upper 1st premolars for therapeutic purpose.

8. Absence of aberrant morphology of roots.

9. Absence of craniofacial malformation.

10. Absence of any supernumerary/supplementary teeth.

Exclusion Criteria

1. History of facial/dental trauma.

2. Root canal treated maxillary canine.

3. Crown and bridge in the upper anterior teeth.

4. Ectopically erupted canine.

5. Systemic disease that requires regular monitoring and medicine intake.

6. Presence of periodontitis.

7. Deleterious oral Habits.

8. Pregnant and lactating women

9. Patients who are currently taking or recently taken NSAIDâ??S, Ibandronates, vitamin D, Relaxin, Calcium, PTH, Progesterone, Insulin, Estrogen, Prostaglandins and Corticosteroids.

10. Patients under medication for hormonal disorders.

11. No history of use of analgesics within the last 3 days before the procedure.

12. Patients with known allergic to nickel.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Amount and type of tooth movement.Timepoint: Days 0,7th,28th,56th and 84th.

Secondary Outcome Measures

Name	Time	Method
Alveolar bone densityTimepoint: days 0 and 84th;Expression level of interleukin â?? 1 beta in Gingival crevicular fluid.Timepoint: Before appliance placement-zero hour, After appliance placement- 1hr, 24hr, 7th day,28th day, 56th day and 84th day.;Pain intensityTimepoint: Before appliance placement-zero hour, After appliance placement- 1hr, 24hr, and followed for 7 days.;The incidence of root resorption.Timepoint: 0 and 84th day