Pharmacokinetics of Tranexamic Acid (TXA) in Children Undergoing Repair of Congenital Heart Defects Utilizing Cardiopulmonary Bypass
Completed
- Conditions
- Congenital Heart Disease
- Registration Number
- NCT01045356
- Lead Sponsor
- Boston Children's Hospital
- Brief Summary
The purpose of this study is to measure blood levels of TXA in children having cardiac surgery which requires cardiopulmonary bypass. TXA is used to reduce bleeding during surgery. This study will help determine if the current dosing of TXA results in therapeutic blood levels.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 55
Inclusion Criteria
- congenital heart disease requiring surgical repair with cardiopulmonary bypass
Exclusion Criteria
- children weighing over 20 kg
- family does not want to participate in the study
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Determine TXA blood levels in children having cardiac surgery with cardiopulmonary bypass. The current dosing recommendations will be utilized. multiple times thoughout surgery
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Children's Hospital Boston
🇺🇸Boston, Massachusetts, United States