Prophylactic Selective Lateral Neck Dissection in Patients With Papillary Thyroid Carcinoma

Not Applicable

Completed

• Conditions: Thyroid Neoplasm; Lymphatic Metastasis

• Registration Number: NCT01103557
• Lead Sponsor: Pusan National University Hospital

Brief Summary

The purpose of this study is to prospectively analyze the incidence of occult lateral neck metastasis (LNM) and to elucidate the factors that predict LNM in papillary thyroid carcinoma (PTC) with central neck metastasis (CNM) by performing prophylactic selective lateral neck dissection (SND).

Detailed Description

The lymphatic drainage pattern of the thyroid is uniform and consistent, and therefore, metastatic patterns are relatively predictable. Initial nodal metastasis in PTC usually occurs in the paratracheal and pretracheal nodes in level VI of the central compartment of the ipsilateral neck and spreads to the lateral cervical lymph nodes. Macroscopic skip metastases to the lateral compartment of the neck in the absence of central disease are uncommon.

Study Timeline

• Status Verified: 2010-01
• Study First Submitted: 2010-04-12
• Study First Submitted QC: 2010-04-13
• Last Update Submitted: 2010-04-13
• Study First Posted: 2010-04-14
• Last Update Posted: 2010-04-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 62

Inclusion Criteria

• Papillary thyroid carcinoma with central neck metastasis
• No evidence of lateral neck metastasis as determined by high-resolution neck ultrasonography and computed tomography

Read More

Exclusion Criteria

• History of previous thyroid operation
• Isthmic thyroid lesion

Read More

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP