Effect of simvastatin on myocardial triglyceride accumulation, cardiac function and vessel wall thickness in patients with type 2 diabetes mellitus - SIMTAC

MC0 个研究点开始时间: 2008年8月5日最近更新: 2012年3月19日

适应症

试验速览

暂无简介。

•diabetes mellitus type 2 treated with metformin alone or in combination with SU-derivate
•HbA1c< 8.5%
•well regulated blood pressure
•BMI >20 kg/m2 and <35 kg/m2
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range

•use of insulin or thiazolidinediones
•use of fibrates or statins one year prior to the study
•hereditary lipoprotein disease
•renal disease: creatinine clearance<60 ml/min or creatinine>100 micromol/l
•allergy to intravenous contrast
•metal implants, claustrophobia or other contraindications for MRI
•any significant chronic disease, hepatic disease or other endocrine disease
•pregnancy/lactation
•psychiatric disorders and/or use of antipsychotic or antidepressant drugs
•recent participation in other research projects in the last 3 months or participation in 2 or more projects in one year

发起方