Stop or Go? Tapering antidepressants in pregnancy: A pragmatic multicenter RCT to investigate risk and benefits for mother and child.

• Conditions: effecten op kind na de geboorte; Depression; depressive disorder; 10026908; 10027946

• Registration Number: NL-OMON44592
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 200

Inclusion Criteria

< 16 weeks pregnant
SSRI use for depressive symptoms

Exclusion Criteria

Multiple pregnancies
Severe medical conditions
Current relapse of depression
Current other severe psychiatric disorders

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Risk of relapse of maternal depressive disorder (as defined by the Structured<br /><br>Clinical Interview for DSM disorders) during pregnancy and up to 3 months<br /><br>postnatal.</p><br>