The Impact of Opioids in Coronary Heart Disease
- Conditions
- Coronary Heart Disease
- Registration Number
- NCT02740621
- Lead Sponsor
- Ruhr University of Bochum
- Brief Summary
In this study, the risk of opioid medications on coronary heart disease in adults is investigated. Patients with the necessity of a coronary angiography and control patients with a non-cardiac disease of the same hospital are inquired with a standardized questionnaire about demographic and clinical risk factors for heart attack. An impact of opioid medications on coronary heart disease is hypothesised (MIOP).
In addition, all patients with coronary angiography should be consulted twice (after 3 and 6 months) to find out how many of these patients have developed a refractory angina pectoris (TRAPS).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 750
- 40 years or older
- written informed consent
- currently cancer
- cognitive limitations
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Number of patients with opioid treatment (WHO II/ WHO III) within the last 10 years before present hospitalization, Interview with standardized CRF 20 minutes Standardized assessment of opioid medications taken before hospital admission to evaluate the impact of opioids in coronary heart disease.
Exact doses, substances and intake habits are inquired.Number of patients with refractory angina pectoris, Interview with standardized CRF 30 minutes Standardized assessment of angina pectoris symptoms and treatments to evaluate a refractory angina pectoris.
Changes of their medications are inquired twice.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Bergmannsheil department of pain therapy
🇩🇪Bochum, Nordrhein-Westfalen, Germany