IRCT20160310026998N12
Recruiting
Phase 3
Assessment of the effect of memantine in the treatment of chemotherapy-induced peripheral neuropathy: double-blind randomized clinical trial
Overview
- Phase
- Phase 3
- Intervention
- Not specified
- Conditions
- chemotherapy-induced peripheral neuropathy in patients with cancer.
- Sponsor
- Tabriz University of Medical Sciences
- Enrollment
- 180
- Status
- Recruiting
- Last Updated
- 5 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •People with any malignancy who have had grade 2 or higher neuropathy following chemotherapy
Exclusion Criteria
- •Patients with hypertension
- •Acute heart failure
- •type 1 \& 2 diabetes mellitus
- •peripheral vascular disease
- •285/5000Patients taking drugs (amantadine, ketamine, dextromethorphan, L\-dopa; dopaminergic, anticholinergic agonists, barbiturates, neuroleptics, IMAO, antispasmodics, dantrolene or baclofen, phenytoinquinotine, cimetidine, ranitidine And warfarin)
- •People of reproductive ages, pregnancy and lactation
- •People taking other neuropathic medications such as gabapentin, pregabalin and dologestin
- •Patients with brain or leptomeningeal metastasis
Outcomes
Primary Outcomes
Not specified
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