Impact of Intermittent Fasting and Mediterranean Diet on the Physical Health of the Elderly: A Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 17
- 试验地点
- 1
- 主要终点
- Biochemical values (mg/dL)
研究概览
简要总结
The prevalence of chronic diseases is increasing globally. In recent years, intermittent fasting has emerged as an effective dietary pattern against some of the most common chronic diseases in the elderly, alongside the Mediterranean diet.
The objective was to determine whether a 12-hour daily intermittent fasting regimen combined with a Mediterranean diet can improve analytical and anthropometric values in the elderly.
A total of 17 individuals of both sexes, over 60 years old, autonomous, and with preserved cognitive capacity participated. They were randomly divided into two groups: 8 people in the intervention group performed intermittent fasting along with a Mediterranean diet, and 9 in the control group adopted only a Mediterranean diet. The intervention lasted 3 months, with measurements taken at the beginning and end of the intervention.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 61 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Over 60 years of age.
- •Belong to the Bombarda health centre.
- •Preserved cognitive capacity.
- •Autonomy for basic and instrumental activities of daily living.
- •Ability to follow a TRF and/or adopt a Mediterranean dietary pattern.
排除标准
- •Underweight (BMI <18.5).
- •Serious or chronic uncontrolled disease.
- •Specific treatment that could alter blood and/or anthropometric values.
- •Poorly controlled type 1 or type 2 insulin-dependent diabetes mellitus.
- •Present or past episode of eating disorder (ED).
- •High alcohol consumption.
结局指标
主要结局
Biochemical values (mg/dL)
时间窗: 12 weeks
Basal glucose, High-Density Lipoprotein, Low-Density Lipoprotein, total cholesterol, triglycerides, serum transferrin, urea, uric acid, creatinine.
Anthropometric values (kg)
时间窗: 12 weeks
Weight
Blood Pressure (mmHg)
时间窗: 12 weeks
Blood pressure (Systolic blood pressure, diastolic blood pressure)
Biochemical values (IU/L)
时间窗: 12 weeks
Alkaline phosphatase, aspartate aminotransferase, alanine aminotransferase, gamma-glutamyltransferase
Biochemical values (mg/L)
时间窗: 12 weeks
C-Reactive Protein
Biochemical values (µg/L)
时间窗: 12 weeks
Serum ferritin
Biochemical values (µg/dL)
时间窗: 12 weeks
Iron
Anthropometric values (cm)
时间窗: 12 weeks
Weight, waist circumference, hip circumference.
Anthropometric values (kg/m^2)
时间窗: 12 weeks
Body mass index.
Anthropometric index (numerical rating scale)
时间窗: 12 weeks
Atherogenic index of plasma, waist/hip ratio.
Biochemical values (g/dL)
时间窗: 12 weeks
Albumin
次要结局
未报告次要终点
研究者
María Isabel Iguacel Azorín
Associate Professor
Universidad de Zaragoza