Age Gender Left Ventricular Mass and Cardiac Troponin T

Completed

• Conditions: Heart Failure

• Registration Number: NCT01100710
• Lead Sponsor: Heidelberg University

Brief Summary

The purpose of this study is to determine the influence of functional or anatomic cardiac parameters, age and gender on high sensitivity cTnT (TnThs) levels in healthy individuals.

Detailed Description

We sought to investigate the relative contribution of functional or anatomic parameters as assessed by cardiac magnetic resonance tomography (cMRI, 1.5 Tesla), and clinical variables including increasing age and gender on high sensitivity cTnT (TnThs) levels in healthy individuals. Therefore we measured TnThs in serum samples of 120 healthy volunteers aged between 20 and 70 years. All individuals underwent cMRI including stress testing using dobutamine or adenosine.TnThs concentrations were related to cMRI and clinical findings. Partial correlation, as well as linear and hierarchical regression analyses were used to identify independent predictors and their relative contribution for prediction of TnThs values.

Study Timeline

• Status Verified: 2007-02
• Study Start: 2007-03
• Primary Completion: 2007-03
• Study Completion: 2009-12
• Study First Submitted: 2010-04-08
• Study First Submitted QC: 2010-04-08
• Last Update Submitted: 2010-04-08
• Study First Posted: 2010-04-09
• Last Update Posted: 2010-04-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 116

Inclusion Criteria

• agreement, age > 18 years, men and women

Exclusion Criteria

• measurable heart disease, any chronic or acute disease, intake of meds, hypertension, Diabetes

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

University Hospital of Heidelberg; 🇩🇪 Heidelberg, Baden-Würtemberg, Germany