THE VALUE OF AUTOFLUORESCENCE ENDOSCOPY FOR THE DETECTION OF EARLY BARRETT*S CANCER

Recruiting

• Conditions: Barrett's cancer; 10017990; 10017991

• Registration Number: NL-OMON32071
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 50

Inclusion Criteria

Patients age >= 18 years scheduled for endoscopy because of recently diagnosed random HGD/EC lesions in Barrett*s Esophagus.

Exclusion Criteria

* Patients unable or unwilling to give informed consent
* Coagulopathy uncorrected at the time of endoscopy or thrombocytopenia (<50 x 109 / l thrombocytes)
* Patients with active reflux esophagitis

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The number of detected HGD/EC lesions in Barrett*s Esophagus in the FQRB by use<br /><br>of video endoscopy compared to the number of detected lesion by the<br /><br>autofluorescence guided targeted biopsy specimens. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>1) The number of biopsy specimens needed to detect one HGD/EC lesion by the use<br /><br>of AFE guided biopsy specimens.<br /><br>2) The number of biopsy specimens needed to detect one HGD/EC lesion by the use<br /><br>of video endoscopy FQRB.<br /><br>3) Duration of the procedure for WLE, AF endoscopy and video endoscopy.</p><br>