Trial to Characterize and Grade the Severity of Capillary Leak Syndrome in Cardiovascular Surgery
- Conditions
- Capillary Leak Syndrome
- Registration Number
- DRKS00017057
- Lead Sponsor
- Klinik für Anästhesiologie und Intensivmedizin, Uniklinik Freiburg
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 405
Inclusion Criteria
1. Cardiac and/or vascular surgery
2. Age =18
3. Consent of the patient, of next-of-kin or legal guardian
Exclusion Criteria
1. Refusal to participate of the patient, of next-of-kin or legal guardian
2. Idiopathic Capillary Leak Syndrome (ICLS, Clarkson's Disease)
3. HIV infection
4. Viral hepatitis
5. Hereditary C1-esterase deficiency
6. Recurrent Angioedema
7. Pre-existing chronic kidney failure on requiring dialysis
8. Pre-existing hepatic impairment with MELD score = 20
9. Participation in pharmacological trials
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method o a priori definition of a primary endpoint is possible in the described study. Goal of this study is to characterize parameters, which may indicate CLS in cardiovascular surgery patients. The occurrence of CLS is evaluated by an experienced critical care physician and scored according to clinical as well as study parameters.
- Secondary Outcome Measures
Name Time Method