NCT00551408已完成不适用
The Determination of Endothelial Progenitor Cells in Pulmonary Idiopathic Arterial Hypertension.
Unidad de Investigacion Clinica en Medicina S.C.1 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2007年8月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 20
- 试验地点
- 1
研究概览
简要总结
Endothelial dysfunction ultimately represents an imbalance between the magnitude of injury and the capacity for repair.
Current evidence established that endothelial progenitor cells (EPC) participate in several models of vascular disease as acute coronary syndromes, stroke, diabetes, peripheral artery disease, etc. However EPC in the setting of PAH is less well established. The target of this study is to demonstrate if the number of EPC is increased in a mexican population of patients with PAH.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients were included in the study if they were in The WHO functional class II to III, and had a mean pulmonary artery pressure >30 mm Hg on right heart catheterization. The ability to walk >50 m during a standardized 6-min walk test.
排除标准
- •Pulmonary hypertension as a result of heart disease, pulmonary disease, sleep-associated disorders, chronic thromboembolic disease, autoimmune or collagen vascular disease, HIV infection, liver disease, major bleeding requiring blood transfusion,renal dysfunction, and evidence for malignant diseases were excluded.
研究者
Dr. Carlos jerjes-Sanchez Diaz
Principal investigator
Unidad de Investigacion Clinica en Medicina S.C.
研究点 (1)
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