ICU Delirium: a One-week Snapshot of Burden Across the Eastern UK Region
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 225
- 试验地点
- 1
- 主要终点
- Delirium prevalence
研究概览
简要总结
ICU delirium negatively impacts on patient outcomes, as well as on resources and clinical workflow of the ICU. Effective healthcare resource planning requires reliable (i.e., multicentre) data that can inform on both of these.
The purpose of this study was to determine the impact of ICU delirium in terms of both patients and beds. The study was carried out prospectively, over a one-week period, at adult ICUs comprising the Norfolk, Suffolk, and Cambridgeshire Critical Care Network (NSC CCN).
详细描述
Previous delirium prevalence research has been carried out at single sites and yielded highly variable results (between 3-87%). Reliable multisite data can be obtained cost-effectively using a point-prevalence ("snapshot") approach.
Purpose: to obtain reliable data informing on prevalence of ICU delirium, in terms of both patients and beds, across the eastern UK region.
Design and Setting: this one-week observational prospective cohort study was carried out between June 25, 2012 (start of ICU day shift) to July 01, 2012 (end of night shift). Nine ICUs comprising the Norfolk, Suffolk, and Cambridgeshire Critical Care Network (NSC CCN) took part. Cambridgeshire 2 Research Ethics Committee approved the study (REC reference: 10/H0308/116) and waived the need for informed consent.
Patients and procedure: All adults treated over the study week at participating ICUs were considered eligible for inclusion. Delirium screening was carried out by patients' direct care clinicians using the Confusion Assessment Method for the ICU (CAM-ICU). All sites used this tool as part of their routine clinical practice and had delirium management guidelines in place at the time of the study. Patients who screened positive for delirium were treated according to local hospital practice.
研究设计
- 研究类型
- Observational
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult patients treated within study time frame on Intensive Care Units across Norfolk, Suffolk, and Cambridgshire, UK
排除标准
- 未提供
结局指标
主要结局
Delirium prevalence
时间窗: June 25, 2012 (start of ICU day shift) to July 1, 2012 (end of ICU night shift)
Number of patients with at least one recorded delirium-positive result, over total number of patients recorded over study time frame. Delirium screening will be carried out using the CAM-ICU by local direct care clinicians in accordance with region-wide clinical delirium-screening guidelines.
次要结局
- Proportion of patient-days with delirium(June 25, 2012 (start of ICU day shift) to July 1, 2012 (end of ICU night shift))
- Median delirium duration(June 25, 2012 (start of ICU day shift) to July 1, 2012 (end of ICU night shift))
- Median days to transition to delirium(June 25, 2012 (start of ICU day shift) to July 1, 2012 (end of ICU night shift))
- Patient age, by delirium status(June 25 (start of ICU day shift) to July 1, 2012 (end of ICU night shift))
- Patient gender, by delirium status(June 25 (start of ICU day shift) to July 1, 2012 (end of ICU night shift))
- Admission type, by delirium status(June 25 (start of ICU day shift) to July 1, 2012 (end of ICU night shift))
- Admission reason, by delirium status(June 25 (start of ICU day shift) to July 1, 2012 (end of ICU night shift))
- Organ support, by delirium status(June 25 (start of ICU day shift) to July 1, 2012 (end of ICU night shift))
- Mobilisation therapy, by delirium status(June 25 (start of ICU day shift) to July 1, 2012 (end of ICU night shift))
- Median ICU days, by delirium status(June 25 (start of ICU day shift) to July 1, 2012 (end of ICU night shift))
- Delirium screening compliance(June 25 (start of ICU day shift) to July 1, 2012 (end of ICU night shift))