Efficacy, safety and action of Microneedling and oral Tranexamic Acid in the treatment of facial Stains.

Not Applicable

Recruiting

• Conditions: Facial melasma (chloasma)Skin disordersWomen; L81.1; M01.975; C16.131.831

• Registration Number: RBR-23snwx
• Lead Sponsor: Escola Paulista de Medicina (EPM/UNIFESP)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-06-16
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

women with mild to severe facial melasma with moderately to severe mMASI clinically proven by a dermatologist titled during the medical visit and who have been untreated for melasma for at least 30 days, except for the use of sunscreen

Exclusion Criteria

other concomitant facial dermatoses, photosensitivity dermatoses, collagenoses, blood dyscrasias or under the use of anticoagulant medication, immunosuppressed; pregnant and lactating women;phenotypic extremes red and black, because melasma is rarely mentioned in these groups. Obese, users of oral contraceptives, sedentary or with a personal or family history of previous thrombotic event have a higher risk of thromboembolism, so will be deallocated from the block with oral tranexamic acid

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Expected outcome 1: reduction of facial melasma pigmentation, verified by variation of the mMASI score of at least 20%, in the before and after intervention measurements (T0 and T60;Expected outcome 2: reduction of facial melasma pigmentation, verified by colorimetric index variation of at least 20% in the before and after intervention measurements (T0 and T60)