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Evaluation of a novel tablet-PC-based number connection test (eNCT)

Conditions
K72.7
Registration Number
DRKS00009432
Lead Sponsor
Charité - Universitätsmedizin BerlinKlinik für Allgemein-, Visceral- und Transplantationschirurgie
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
238
Inclusion Criteria

1. healty subjects (at least 18 years old)
2. patients (at least 18 years old) with histologically confirmed liver cirrhosis of every reasons (including alcoholic liver disease) or who are suspected to have liver cirrhosis because of existence of complications like ascites, varices, hepatic encephalopathy or increased part of connective tissue in the liver.
3. no florid abuse of alcohol or drugs in the last 6 months before study inclusion.
4. patients who gave there informed consent in written form

Exclusion Criteria

1. mini-mental status score <25
2. known impairment of red and green vision
3. known neurological/psychiatric disease which affects the cognitive performance (besides hepatic encephalopathy)
4. knwon neurological/psychiatric disease with intake of medicine that affects the central nervous system (e.g. benzodiazepines or some sleeping pills)

Study & Design

Study Type
observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
test validity: correlation of the newly developed eNCT results with test times of well-established paper-pencil tests of the Psychometric Hepatic Encephalopathy Score test battery
Secondary Outcome Measures
NameTimeMethod
test-retest-reliability; participants repeat the test procedure twice, with at least 4 days between the test and retest
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