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临床试验/NCT03272022
NCT03272022已完成不适用

Micronutrient Status in Pregnant and Lactating Women and Their Infants

Haukeland University Hospital0 个研究点目标入组 272 人开始时间: 2011年12月14日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
272
主要终点
Change in micronutrient status during pregnancy and lactation

研究概览

简要总结

An adequate micronutrient status during fetal life and infancy is important for optimal development. Dietary practices during pregnancy, lactation and infancy vary among populations and there is today no clear agreement on what constitutes the best diet, including micronutrient supplementation, during this period. There is consequently no clear agreement on what constitutes an optimal biochemical micronutrient status in mothers and infants. Due to substantial physiological changes in plasma volume, hormones, transport proteins and organ function during these periods, the ordinary reference levels or cut off levels used for biochemical assessment of micronutrient status are unsuited to these groups of patients.

The objective of the study is to establish cut off levels for important vitamins and trace elements during pregnancy, lactation and infancy in order to ensure an optimal infant neurodevelopment and to study how micronutrient status influence the immunosystem.

详细描述

The investigators have analyzed micronutrients, including all vitamins and trace elements and related aminoacids and markers of cellular immunoactivation in 160 fertile, unpregnant women, 115 pregnant women from pregnancy week 18, throughout pregnancy and the first 6 postpartum months and their infant at 6 months. Infant gross motor development is associated with micronutrient status, so the investigators will relate gross motor development at 6 months to maternal micronutrient status during pregnancy and postpartum, in order to establish relevant cut off levels for micronutrients and related biomarkers.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 40 Years(Adult)
性别
Female
接受健康志愿者

入选标准

  • healthy never-pregnant and pregnant women

排除标准

  • chronic illness-

结局指标

主要结局

Change in micronutrient status during pregnancy and lactation

时间窗: The investigators will study change in micronutrients during pregnancy and lactation

Determine adequate vitamin levels in pregnancy and lactation

次要结局

未报告次要终点

研究者

发起方
Haukeland University Hospital
申办方类型
Other
责任方
Sponsor

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