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Gum reconstruction by using injectable hyaluronic acid

Recruiting
Conditions
Periodontal Condition
Registration Number
CTRI/2025/04/085597
Lead Sponsor
Parveen Dahiya
Brief Summary

This study will investigate the effect of hyaluronic acid gel injections on interdental papilla without comparing it to other treatments. The effectiveness will be evaluated over a three-month period by measuring the reduction in black triangle height using photographic analysis. Hyaluronic acid, a nonimmunogenic substance, activates cellular processes such as migration, proliferation, and gene expression. A larger sample size than previous studies will be used, with treatment indicated when the bone crest-to-contact point distance exceeds 5 mm, as recommended by Norland and Tarnow 1998. All participants will receive full-mouth scaling and polishing one week before treatment to ensure tissue healing and reduce inflammation. Local anesthesia will be applied at the mucogingival junction before hyaluronic acid  injection to avoid interference with hyaluronic acid and reduce tissue punctures. A second hyaluronic acid injection will be administered after three weeks to reinforce the initial effect, based on manufacturer guidelines and previous studies. A follow-up evaluation will be conducted three months after the initial injection.

Detailed Description

Not available

Recruitment & Eligibility

Status
Open to Recruitment
Sex
All
Target Recruitment
15
Inclusion Criteria
  • Non-smoking patient.
  • Had at least one site with interdental papilla recession in the anterior region of the maxillary and mandibular jaws.
  • No active periodontal diseases and good oral hygiene.
Exclusion Criteria
  • If patient have spacing or crowding between the teeth to be treated, abnormal tooth shape, systemic diseases such as diabetes mellitus, hypertension or conditions that alter the outcome of periodontal therapy.
  • Pregnant and lactating women and tobacco users excluded.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
inter-papillary regeneration3 months
Secondary Outcome Measures
NameTimeMethod
subject perspective towards esthetic zone3 months

Trial Locations

Locations (1)

Himachal institute of dental sciences, paonta sahib

🇮🇳

Sirmaur, HIMACHAL PRADESH, India

Himachal institute of dental sciences, paonta sahib
🇮🇳Sirmaur, HIMACHAL PRADESH, India
Dr Sagarika Surya
Principal investigator
8077762039
sagarika.surya@gmail.com

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