Temporal-Spatial Modality Research for the Mechanism of Acupuncture Therapy on Limb Numbness in Chronic Stroke Based on Complex Brain Network

DongzhimenHospital of Beijing University of Chinese Medicine0 个研究点开始时间: 待定最近更新: 2023年2月20日

试验速览

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•1. Rxperiment group: Patients with stroke sequelae and limb numbness
•Diagnostic criteria: Chinese guideline for the prevention and treatment of cerebrovascular diseases, 2007.
•(1) meet the diagnostic criteria of stroke;
•(2) confirm that the responsible focus is located in the subcortical area by imaging (MRI);
•(3) onset time: 6 months to 5 years;
•(4) accompanied by clinical manifestations of unilateral limb numbness;
•(5) muscle strength of the affected side of limb above level 3;
•(6) right handedness;
•(7) aged between 30-75 years men and women;
•(8) not accompanied by consciousness disorder, hearing and vision, cognitive and mental disorders, the condition;
•(9) not taking psychoactive drugs in the past month.
•2. Control group: age and sex matched healthy population:
•(1) right handedness;
•(2) aged between 30-75 years old, male and female;
•(3) physical examination shows that it belongs to the range of physical health, without organic and significant functional diseases;
•(4) no central nervous system, serious mental and physical diseases, no history of drug and alcohol dependence;
•(5) no infectious disease abnormalities (such as cold, headache, cough, etc.) in the experimental stage;
•(6) voluntary participation in this study and with stable emotional state.

•1. cerebral infarction or intracerebral hemorrhage in cortex;
•2. intracranial space occupying lesions, inflammation, craniocerebral trauma, epilepsy, etc.; other causes of brain white matter lesions and neurodegenerative diseases, etc.;
•3. diabetic peripheral neuropathy, peripheral neuropathy and other diseases, combined with serious medical diseases;
•4. mental diseases and serious cognitive disorders;
•5. allergic constitution, easy to be combined Those with infection and bleeding; pregnant women, lactating women and menstrual women;
•6. those who can't understand the cooperation examination or have other MRI examination taboos such as claustrophobia;
•7. those who find serious skull anatomical structure asymmetry or definite lesions in MRI scanning.

发起方

DongzhimenHospital of Beijing University of Chinese Medicine