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Vestibulotoxicity in consequence of tobramycin therapy in cystic fibrosis patients

Phase 4
Recruiting
Conditions
damage of the inner ear
disturbance of equilibrium
10022396
Registration Number
NL-OMON29992
Lead Sponsor
HagaZiekenhuis
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Not specified
Target Recruitment
40
Inclusion Criteria

cystic fibrosis patients currently known in the HAGA hospital who have been treated at least one time with intravenous tobramycin and with an audiogram in medical dossier

Exclusion Criteria

patients treated with other intravenous aminoglycoside therapy than tobramycine
patients receiving intravenous aminoglycosides during investigation.
patients with perforation of one of the tympanic membranes.
patients with a radical cave.

Study & Design

Study Type
Observational invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>Primary study parameter is formulated as whether there is damage to the<br /><br>vestibulum or there is not. </p><br>
Secondary Outcome Measures
NameTimeMethod
<p>Secundary study parameter is formulated as whether there is disturbance of<br /><br>equilibrium due to damage of the vestibulum or there is not.</p><br>
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