Evaluation the comparison efficacy of topical DEMUlcent La' farrerr Cream with Diclofenac 1% gel on improvement of pain in patients with knee joint osteoarthritis
Phase 3
Recruiting
- Conditions
- osteoarthritis of knee joint.Osteoarthritis of knee
- Registration Number
- IRCT20240210060954N1
- Lead Sponsor
- Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 284
Inclusion Criteria
patients with knee osteoarthritis (OA) with Kellegren-Lowrence garde 1-3
participants with knee joint osteoarthritis
38 to 65 years old
Exclusion Criteria
were pregnant or lactating
had received NSAIDs, anti inflammatory treatment including oral and topical forms
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain level. Timepoint: baseline, 14th, and the end of the study. Method of measurement: visual analogue scale (VAS).;Evaluate knee joint pain. Timepoint: baseline, 14th, and the end of the study. Method of measurement: Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) questionnaire.;Evaluate knee joint stiffness. Timepoint: baseline, 14th, and the end of the study. Method of measurement: WOMAC questionnaire.;Evaluate physical function. Timepoint: baseline, 14th, and the end of the study. Method of measurement: WOMAC questionnaire.
- Secondary Outcome Measures
Name Time Method Evaluate Adverse event. Timepoint: During the study. Method of measurement: self-reporting.