Comparision of pain relief in breast cancer patients by giving full body anesthesia with nearby local injection of drugs bupivacaine along with dexmeditomidine with ultrasound in one group and full body anesthesia alone in other group of patients.

Not yet recruiting

• Conditions: Medical and Surgical, (2) ICD-10 Condition: O||Medical and Surgical,

• Registration Number: CTRI/2019/04/018394
• Lead Sponsor: SRI RAMAKRISHNA HOSPITAL

Brief Summary

BACKGROUND AND AIMS: Breast cancer is the most common cause in women worldwide with morethan 1 million new cases diagnosed every year. Acute post operative pain following mastectomy remains a challenge for the anaesthesiologist despite a range of treatment options available. The present study aimed to compare the post operative analgesic efficacy of PECS block and serratus anterior plane block performed under ultrasound with our standard practise of opioids and non-steroidal anti-inflammatory drugs for mastectomy. 

METHODS: Randomised controlled study to be conducted in our hospital after obtaining ethical clearence 60 adult female patients posted for elective unilateral modified radical mastectomy to be divided in to 2 groups as follows. Group S- general anesthesia with out block. Group BD- general anesthesia with PECI, PECII,and Serratus anterior plane block with 30ml of 0.25% Bupivacaine with 0.5mcg/kg bodyweight of Dexmeditomidine.Primary outcome to be measured as patient reported pain intensity using VAS at rest.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2019-03-25
• Study Start: 2019-09-30

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: Female
• Target Recruitment: 60

Inclusion Criteria

• 1.ASA I and II patients.
• 2.patients coming for elective breast surgeries.
• 3.patients who provide consent for the study.

Exclusion Criteria

• 1.ASA III and above.
• 2.patient refusal.
• 3.patients allergic to study drug.
• 4.patient who are pregnant, patient on any antidepressant, antipsychotics drugs.
• 5.prior breast surgeries except for dianostic purpose.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1.To determine the time for 1st rescue analgesia.	30/3/2019
2.Total rescue analgesia consumed over 24 h period was recorded.	30/3/2019

Secondary Outcome Measures

Name	Time	Method
1.Incidence of hypotension and bradycardia.	2.Incidence of PONV and pruritus

Trial Locations

Locations (1)

SRI RAMAKRISHNA HOSPITAL; 🇮🇳 Coimbatore, TAMIL NADU, India

SRI RAMAKRISHNA HOSPITAL

🇮🇳Coimbatore, TAMIL NADU, India

K SAI LAKSHMI

Principal investigator

9849914525

sailakshminmc@gmail.com