Comparison of Postoperative Analgesic Efficacy of Intravenous Dexketoprofen Trometamol With Tenoxicam in Lumbar Disc Surgery
试验速览
- 阶段
- 4 期
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- analgesic consumption
研究概览
简要总结
In this study the investigators aimed to compare of postoperative analgesic effects of intravenous dexketoprofen trometamol and tenoxicam in lumbar disc surgery.
详细描述
Lumbar disc surgery is associated with moderate to severe back and radicular pain postoperatively which has unfavorable effects on patients recovery and procedures outcome. Dexketoprofen has been reported to be one of the NSAİDs that can provide good results when compared with narcotics in many painful conditions and especially in the treatment of the moderate to severe postoperative pain that may develop after lumbal disc surgery. Tenoxicam is a thienothiazine derivative of the oxicam class of NSAİDs. There are some studies in which NSAİDs have been used to together with opioids for postoperative analgesia showing that they decrease opioid consumption and side effects
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •between 18-65 age
- •elective lumbar disc surgery
排除标准
- •history of gastrointestinal bleeding
- •peptic ulcer disease
- •bleeding disorders
- •history of allergic reactions to NSAİDs
- •chronic pain syndrome
研究组 & 干预措施
dexketoprofen trometamol
before end of the surgery via intravenous administration 50 mg dexketoprofen trometamol in 0.9 % NaCl 100 cc
干预措施: dexketoprofen trometamol (Drug)
tenoxicam
before the end of the surgery via administration intravenous 20 mg tenoxicam in 0.9% NaCl in 100 cc
干预措施: tenoxicam (Drug)
serum physiologic
before end of the surgery via administration intravenous 0.9 % NaCl 100 cc
干预措施: serum physiologic (Drug)
结局指标
主要结局
analgesic consumption
时间窗: postoperative 1 day
morphine consumption (patient control analgesia procedure) was recorded
次要结局
- visual analog scale(postoperative 1 day)
研究者
Nazife Küçük
resident
TC Erciyes University