Comparison of Postoperative Analgesic Efficacy of Intravenous Dexketoprofen Trometamol With Tenoxicam in Lumbar Disc Surgery
Overview
- Phase
- Phase 4
- Intervention
- dexketoprofen trometamol
- Conditions
- Postoperative Pain
- Sponsor
- TC Erciyes University
- Enrollment
- 90
- Locations
- 1
- Primary Endpoint
- analgesic consumption
- Last Updated
- 11 years ago
Overview
Brief Summary
In this study the investigators aimed to compare of postoperative analgesic effects of intravenous dexketoprofen trometamol and tenoxicam in lumbar disc surgery.
Detailed Description
Lumbar disc surgery is associated with moderate to severe back and radicular pain postoperatively which has unfavorable effects on patients recovery and procedures outcome. Dexketoprofen has been reported to be one of the NSAİDs that can provide good results when compared with narcotics in many painful conditions and especially in the treatment of the moderate to severe postoperative pain that may develop after lumbal disc surgery. Tenoxicam is a thienothiazine derivative of the oxicam class of NSAİDs. There are some studies in which NSAİDs have been used to together with opioids for postoperative analgesia showing that they decrease opioid consumption and side effects
Investigators
Nazife Küçük
resident
TC Erciyes University
Eligibility Criteria
Inclusion Criteria
- •between 18-65 age
- •elective lumbar disc surgery
Exclusion Criteria
- •history of gastrointestinal bleeding
- •peptic ulcer disease
- •bleeding disorders
- •history of allergic reactions to NSAİDs
- •chronic pain syndrome
Arms & Interventions
dexketoprofen trometamol
before end of the surgery via intravenous administration 50 mg dexketoprofen trometamol in 0.9 % NaCl 100 cc
Intervention: dexketoprofen trometamol
tenoxicam
before the end of the surgery via administration intravenous 20 mg tenoxicam in 0.9% NaCl in 100 cc
Intervention: tenoxicam
serum physiologic
before end of the surgery via administration intravenous 0.9 % NaCl 100 cc
Intervention: serum physiologic
Outcomes
Primary Outcomes
analgesic consumption
Time Frame: postoperative 1 day
morphine consumption (patient control analgesia procedure) was recorded
Secondary Outcomes
- visual analog scale(postoperative 1 day)