Re-Adjustment of Sweep Gas Flow to the During the Rewarming Period of the Cardiopulmonary Bypass

Recruiting

• Conditions: Optimal Sweep Gas Flow; Determination of Optimal Sweep Gas Flow for Different Phases of Cardiopulmonary Bypass

• Registration Number: NCT06013189
• Lead Sponsor: Acıbadem Atunizade Hospital

Brief Summary

The investigators designed this prospective observational study with the theory that alkalosis caused by decreased CO2 solubility due to temperature increase during the rewarming period of the Cardiopulmonary Bypass could be prevented by reducing the sweep gas flow during the rewarming period.

Detailed Description

Not available

Study Timeline

• Status Verified: 2023-08
• Study Start: 2023-08-07
• Study First Submitted: 2023-08-16
• Study First Submitted QC: 2023-08-24
• Last Update Submitted: 2023-08-24
• Study First Posted: 2023-08-28
• Last Update Posted: 2023-08-28
• Primary Completion: 2023-11-01
• Study Completion: 2034-11

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

• Patients over 18 years of age
• Elective CPB surgery

Exclusion Criteria

• Patients undergoing minimally invasive surgery
• Patients undergoing robotic cardiac surgery,
• Patients undergoing deep hypothermia,
• Patients undergoing total circulatory arrest,
• Patients whose FiO2 requirement is high that cannot be applied to target gas flow

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Arterial pH lever lower than 7.30	during the cardiopulmonary bypass and postoperative 24th hour	maintaining physiological pH

Secondary Outcome Measures

Name	Time	Method
rSO2 20% below initial value	during the cardiopulmonary bypass	observing the rSO2 of brain during rewarming period

Trial Locations

Locations (1)

Acıbadem Altunizade Hastanesi İstanbul; 🇹🇷 Istanbul, Altunizade, Turkey