Optimal concentration of Ropivacaine for transverse thoracic muscle plane block for adult open heart surgery - TTPB Study

Tachi Keitaro0 个研究点目标入组 70 人开始时间: 2024年1月22日最近更新: 2024年4月23日

试验速览

暂无简介。

•1) Patients undergoing cardiac surgery under median sternotomy.
•2) Patients with American Society of Anesthesiologist(ASA)-physical status classification II-IV.
•3) Patients who are 18 years old or older and younger than 80 years old at the time of obtaining consent.
•4) Patients who have been fully informed of the study and who have given written consent of their own free will.

•Patients with the following conditions will be excluded from the study
•1) Previous median sternotomy
•2) Deformity near the sternum (e.g., funnel chest)
•3) Neuropathy near the puncture site
•4) Nerve block puncture site infection
•5) History of allergy to local anesthetics or drugs used for general anesthesia
•6) Pregnancy
•7) Emergency surgery
•8) Heart failure with NYHA Classification IV symptoms
•9) Pulmonary hypertension requiring inhalation of nitric oxide
•10) Preoperative ventilatory management
•11) Serious blood coagulation disorder (platelet count less than 50000/mcL, PT% less than 60%, APTT 15 seconds longer than control value)
•12) Patients with serious systemic diseases
•13) Cases of infective endocarditis
•14) Patients on drugs that inhibit CYP1A2
•15) Other patients deemed inappropriate as subjects by the investigator

发起方

Tachi Keitaro