Comparison between two drugs- dexmedetomidine and lidocaine, when administered via two routes- nebulized and intravenous as a premedication for awake fibreoptic intubation in attenuating the haemodynamic changes and for patient comfort

Phase 4

Not yet recruiting

• Conditions: Malignant neoplasm of overlappingsites of lip, oral cavity and pharynx,

• Registration Number: CTRI/2022/03/041006
• Lead Sponsor: Reshma Jose

Brief Summary

This is a prospective, double blind study to compare the efficiency of nebulized dexmedetomidine - lidocaine mixture and intravenous dexmedetomidine - lidocaine nebulization as a premedication for awake fibreoptic intubation in head and neck surgeries in Mazumdar Shaw Medical Centre, Bangalore. The primary objective is to measure the patient comfort in terms of cough score. The secondary outcome will be the comparison of incidence of bradycardia and hypotension in between the two study groups.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-01-04
• Last Update Posted: 2022-05-05

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 54

Inclusion Criteria

ASA 1 and 2 patients between 18 to 65 years planned for elective fibreoptic intubation in head and neck surgeries in Mazumdar Shaw Medical Centre, Bangalore.

Exclusion Criteria

Patient refusal Pregnancy Known cardiac diseases including heart block Intracranial pathology and cerebrovascular diseases.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Comparison of patient comfort in terms of cough score	10 minutes

Secondary Outcome Measures

Name	Time	Method
Incidence of bradycardia and hypotension	10 minutes

Trial Locations

Locations (1)

Mazumdar Shaw Medical Centre, Narayana Hrudayalaya Hospital; 🇮🇳 Bangalore, KARNATAKA, India

Mazumdar Shaw Medical Centre, Narayana Hrudayalaya Hospital

🇮🇳Bangalore, KARNATAKA, India

Reshma Jose

Principal investigator

9742581820

reshmajose010@gmail.com