Alpha-1-Antitrypsin Deficiency in a Diverticular Disease Populatio
Recruiting
- Conditions
- diverticular disease (DD) alpha-1-antitrypsin (A1AT) pathology
- Registration Number
- NL-OMON28920
- Lead Sponsor
- -
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 230
Inclusion Criteria
Research group: the subject has to
-Have acute abdominal pain existing more than two hours’ and less than five days,
Exclusion Criteria
A potential subject who meets any of the following criteria will be excluded from participation in this study:
-Does not meet the inclusion criteria
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The main exposure factor is of alpha-1-antitrypsin pathology
- Secondary Outcome Measures
Name Time Method Secondary exposure factors are:<br /><br>- Concentration of alpha-1-antitrypsin <br /><br>- Inflammation parameters <br /><br>- Risk factors for developing diverticulosis such as<br /><br>•Genetic factors<br /><br>oFamily history<br /><br>•Environmental factors:<br /><br>oLow-fiber diet<br /><br>oObesity<br /><br>o Decreased physical activity<br /><br>oUse of corticosteroids<br /><br>oUse of NSAIDs<br /><br>oAlcohol<br /><br>oCaffeine intake<br /><br>oCigarette smoking<br /><br>oPolycystic kidney disease<br /><br>•Epidemiological factors<br /><br>oAge<br /><br>oGeography<br /><br>oLife style<br /><br>oEthnicity<br /><br>