JPRN-UMIN000005654招募中2 期
The Efficacy and Feasibility Study of Neoadjuvant Chemotherapy without Radiotherapy for Locally Advanced Rectal Cancer (Est-Neo) - The Efficacy and Feasibility Study of Neoadjuvant Chemotherapy without Radiotherapy for Locally Advanced Rectal Cancer
Gastro-intestinal Sugery Division, Kyoto University Hospital0 个研究点目标入组 55 人开始时间: 2011年6月1日最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 招募中
- 发起方
- 入组人数
- 55
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 20years-old 至 80years-old(—)
- 性别
- All
入选标准
- 未提供
排除标准
- •# Distant metastases # Cerebrovascular disease (CVD) with paralytic symptoms or prior CVD within one year. # Symptomatic or actively treated cardiac disorders. Or prior cardiac disorder within one year. # Cancerous fluid on diagnostic imaging. # Prior chemotherapy or pelvic irradiation for malignancy. # Other cancer diagnosis within the past 5 years (including colorectal cancer). # Interstitial pneumonia or fibroid lung. # Uncontrolled infection. # Current symptoms of neuropathy, defined as >= grade 2 neurosensory or neuromotor toxicity. # Ileus (cases with diverting stoma are eligible). # Uncontrolled diarrhea. # Pregnant, nursing or no intention to contraception. # Contraindication for the administration of bevacitumab (In the cases of KRAS mutant-type) # Those considered inappropriate for participation in this trial.
研究者
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