ACTRN12610000245099尚未招募4 期
Effects of Parecoxib, a selective cyclooxygenase-2 inhibitor,on liver function in Patients Undergoing hepatectomy of hepatic carcinoma: A Double-Blind, Randomized, Comparative Study
jinmin zhang0 个研究点目标入组 60 人开始时间: 2010年3月24日最近更新:
适应症
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 70 Years（—）
- 性别
- All
入选标准
- •1.elective liver resection 2. American Society of Anesthesiologists (ASA) physical status 2-3 patients 3.Primary liver cancer patients who had history of hepatitis B related cirrhosis 4.undergoing combine general and epidural anesthesia
排除标准
- •1contradictions of epidural puncture including coagulate disorder (prothrombin time (PT) longer than 15 sec or/and blood platelets count less than 10,000 ).
- •2.tumor size too small or too large(longitude of tumor was beyond 3-8 cm ) or estimated blood loss was large than 1000 cc.
- •3.Individuals in whom the regional block failed and surgery was performed under general anesthesia alone were also withdrawn from the study..
- •4.Patients with a known allergy to NSAIDs
- •5.Patients who had received chemotherapy and radiation prior to surgery
- •6.patients who with a history of peptic ulceration, or renal, cardiac, endocrine
- •7. Patients who had received Non steroidal anti-inflammatory drugs (NSAIDs) within 14 days before enrollment
研究者
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