ACTRN12614001189617已完成未知
Short-Term Exenatide Therapy in Hyperglycaemia and Acute Ischaemic Stroke - A Randomised, Open-Label, Parallel-Group Study to Determine the Effect of Exenatide on Blood Glucose Levels
orthern Sydney Local Health District0 个研究点目标入组 30 人开始时间: 2014年11月12日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 30
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- All
入选标准
- •Patient presenting with acute ischaemic stroke, as confirmed by routine neurological assessment
- •- Blood glucose level > 10mmol/L on blood glucose testing during the first 72 hours after admission to the Acute Stroke Ward
- •- Age > 18 years
排除标准
- •- Type 1 diabetes mellitus
- •- Initial NIHSS > 20
- •- Life expectancy below 12 months
- •- Pre morbid modified Rankin Score above 3
- •- Impaired liver function, defined as alanine aminotransferase (ALT) > 3 times the upper limit of normal
- •- Impaired renal function, defined as eGFR < 30 ml/min/1.73m2
- •- History of pancreatitis
- •- History of pancreatic cancer
- •- History of medullary thyroid cancer or multiple endocrine neoplasia II
- •- Known allergy to exenatide
- •- Suspected or known abuse of alcohol or narcotics
- •- Pregnancy or lactation
研究者
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