The Relationship Between Pre-pregnancy BMI and Weight Gain and Outcomes in Women With Twin Pregnancy

• Conditions: Twin Pregnancy; Body Mass Index; Weight Gain; Pregnancy Outcome
• Interventions: Other: collect date about all participants

• Registration Number: NCT04777903
• Lead Sponsor: Second Affiliated Hospital of Wenzhou Medical University

Brief Summary

Prepregnancy body mass index (BMI) and gestational weight gain (GWG) have Significant effects on the risk of pregnancy outcomes such as gestational hypertension disease and gestational diabetes mellitus in singleton pregnancies. This paper is to investigate the relationship between pre-pregnancy body mass index (BMI) and weight gain during pregnancy and pregnancy outcomes in women with twin pregnancy.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-01-01
• Primary Completion: 2020-12-31
• Status Verified: 2021-02
• Study First Submitted: 2021-02-28
• Study First Submitted QC: 2021-03-01
• Last Update Submitted: 2021-03-01
• Study First Posted: 2021-03-02
• Last Update Posted: 2021-03-02
• Study Completion: 2021-06-30

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 250

Inclusion Criteria

• Age 18 ~ 41 years old;
• The gestational age of the first diagnosed twin pregnancy is ≤10weeks;
• Double chorionic double amniotic sac pregnancy;

Exclusion Criteria

• with heart disease, liver disease, kidney disease, complications (chronic hypertension, hyperthyroidism, diabetes and others ), genetic diseases, psychological and mental diseases;
• with history of habitual abortion and cervical insufficiency;

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
overweight and obese woman with twin pregnancy	collect date about all participants	overweight and obese (BMI ≥24 kg/m2)
underweight woman with twin pregnancy	collect date about all participants	underweight (BMI \< 18.5 kg/m2)
normal weight woman with twin pregnancy	collect date about all participants	normal (BMI: 18.5-23.9 kg/m2)

Primary Outcome Measures

Name	Time	Method
the incidence of gestational diabetes mellitus, gestational hypertension and small for gestational age	35 weeks to 40 weeks gestation	pregnant outcome

Trial Locations

Locations (1)

department of obstetrics of Second Affiliated Hospital of Wenzhou Medical University; 🇨🇳 Wenzhou, Zhejiang, China